Effect and function of Ganmaoqing Capsule|Hunan Zhongcheng Pharmaceutical Machinery Factory

[Prescription] South Banlangen 940g Daqingye 400g Jinqi silver plate 660g Gangmei 860g Mountain sesame 460g Acetaminophen 24g Andrographis 40g Hydrochloride morpholinium 24g Maleic acid chlorpheniramine 1g

[Method] The above nine flavors, take Jinshao Yinpan, Daqingye, Gangmei, South Banlangen, Mountain Sesame, add water to cook twice, * 2 hours, 2 hours for the second time, combined with decoction, filtered The filtrate is concentrated to a relative density of 1.15 (60 ° C), ethanol is added to an alcohol content of 50% or more, allowed to stand, filtered, and the filtrate is recovered into ethanol, concentrated to a thick paste, and dried at 80 ° C or lower to prepare a dry extract. . Take dry extract, acetaminophen, chlorpheniramine maleate, morpholinium hydrochloride and andrographis paniculata, respectively, into fine powder, sieve, mix, add ethanol and auxiliary materials, mix well, make four The color particles were filled into capsules and made into 1000 tablets. That is.

【Properties】 This product is a capsule, the content is four-color particles; bitter taste.


(1) Take the contents of 10 capsules of this product, grind finely, add 15ml of ethanol, reflux on the water bath for 15 minutes, let cool, add 1g of activated carbon, heat for a few minutes, filter, and take 2ml of the filtrate into two test tubes. . 2 drops of a mixture of dinitrobenzoic acid test solution and potassium hydroxide test solution in one tube, showing a purple-red color; adding 6 drops of 5% sodium nitrite test solution to another tube, and letting it stand for 6 minutes. Add 6 drops of 10% aluminum nitrate test solution, then place for 6 minutes, then add 6 drops of sodium hydroxide test solution, which is red.

(2) Take the filtrate remaining under [Identification] (1) as the test solution. Medical teaching. Yu network collection and preparation of another chlorpheniramine maleate reference substance, morpholinium hydrochloride reference substance, respectively, add ethanol to make perml containing chlorpheniramine maleate 0.2mg, containing morpholinium hydrochloride 10mg The solution was used as a reference solution. According to the thin layer chromatography (Appendix IVB) test, 5 μl of each of the above three solutions was taken up and spotted on the same silica gel G thin layer plate, and the ethanol-water-concentrated ammonia solution (50:50:1) was used as the developing agent. Take out, dry, and smoke with iodine vapor. In the chromatogram of the test sample, spots of the same color are respectively displayed at positions corresponding to the chromatograms of the above two reference materials.

(3) Take the appropriate amount of acetaminophen reference substance and test according to the method of content determination. The retention time of the main peak of the test sample should be consistent with the retention time of the acetaminophen reference substance.

[Check] should comply with the relevant provisions under the capsule (Appendix IL).

【Functions and Indications】Dissolve the wind, clear the heat and detoxify. For wind-heat cold, fever, headache, nasal congestion, sneezing, sore throat, body aches and other symptoms.

[Usage and Dosage] Oral, 1 to 2 capsules at a time, 3 times a day.

[Note] It is not advisable to drive the vehicle, manage the machine and work at height during the medication.

[Specification] 0.5g per capsule (containing acetaminophen 24mg)

[Storage] Sealed.

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