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CAS No.2156-56-1
Chemical Name:Sodium dichloroacetate
SynonymsSDA;dichloroctansodny;NATRIUMDICHLORACETAT;Sodiumdichloracetate;SODIUM DICHLOROACETATE;Dichloroacetate Sodium;Sodiumdichloroacetate,97%;SODIUM DICHLOROACETIC ACID;dichloroacetate,sodiumsalt;Sodium 2,2-dichloroacetate
CBNumber:CB0695718
Molecular Formula:C2HCl2NaO2
Formula Weight:150.92
Chemical Properties
white powder
Biological Activity
Inhibitor of mitochondrial pyruvate dehydrogenase kinase (PDK). Shifts pyruvate metabolism from glycolysis and lactate production to glucose oxidation in the mitochondria. Induces mitochondrial-dependent apoptosis and reverses the inhibition/downregulation of KÂ V 1.5 channels in cancer but not normal cells. Decreases tumor growth in vitro and in vivoÂ
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