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Olaparib (AZD2281, Ku-0059436) is a selective PARP1 / 2 inhibitor with an IC50 of 5 nM / 1 nM in cell-free assays, 300-fold stronger than that of Tankyrase-1. Phase 3
Chemical Name : 4-(3-(1-(cyclopropanecarbonyl)piperazine-4-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one
MF: C24H23FN4O3
CAS No:763113-22-0
MW: 434.469
Purity: 99%min
Appearance: White Powder
Application: API
Solubility (25°C) : DMSO 86 mg/mL warming (197.94 mM) Water 0.002 mg/mL (0.0 mM) Ethanol <1 mg/mL
Stability :-20ºC Powder , 3 years : -80ºC Soluble in solvents 2years
Type: Antineoplastic Agents
Grade Standard: Medicine Grade
Description
Olaparib is a prescription medicine used to treat advanced Ovarian cancer, It is for patients whose cancerhas certain mutations in the BRCA1 and BRCA2 genes and who have already been treated with at least three other types of chemotherapy.Olaparib is also being studied in the treatment of other types of cancer.
Olapanil is a novel poly-ADP ribose polymerase (PARP) inhibitor, including PARP1, PARP2, and PARP3. PARP mediates a mechanism of DNA repair and plays an important role in DNA damage repair and cell apoptosis. Therefore, the mechanism of DNA damage repair by targeting to cells is mediated by PARP1 and PARCA2 mutant cancer cells Of the critical loopholes in the role, can be used for breast cancer susceptibility gene (BRCA) mutations, platinum-sensitive drug-resistant patients with recurrent severe ovarian cancer maintenance therapy.
Olaparib is a kind of novel poly ADP-ribose polymerase (PARP) inhibitors, including PARP1, PARP2, and PARP3. PARP mediates a DNA-repair mechanism which plays a important role in DNA damage repair and apoptosis, so olaparib specifically targets on the DNA repair mechanism of the targeting cell DNA repair and take effects by attacking the critical vulnerabilities of cancer cells carrying mutations in BRCA1 and BRCA2. Owing to this mechanism, it can be used for the maintenance therapy of patients of severe recurrent ovarian cancer who has breast cancer susceptibility gene (BRCA) mutation as well as being sensitive to platinum drug.
Before order:
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1.you could contact us by emial,whatsapp,skype.I am online all the time
2.tell me how many your need and your requirement about products and shipping
3.we offer product COA,Penicillin bottles;cook recipes and others customers tracking numbers and anything if you need.
4.we are accpet Western union,Bank transfer, Bitcion,Money gram,Alipay,Credit card.
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Packing Details:
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1.Packages are generally dispatched within approximately 2Â days after receipt of payment.
2.After the each shipping we will provide you with: tracking number;pictures with your parcel;
3.Delivery Ways:EMS,HKEMS,TNT,DHL,FedEX,UPS etc.
4.Most countries can arrived within 5-10 days
Â
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SARM
Peptides
Ostarine (MK-2866)
MGF
Cardarine (GW-501516)
PEG MGF
Andarine (S4)
CJC-1295 with DAC
Ligandrol (LGD-4033)
CJC-1295 without DAC/GRF(1-29)
Ibutamoren (MK-677)
PT-141
RAD140
MT-2/Melanotan II
SR9009
Â
YK11
GHRP-6
S-23
Ipamorelin
GW-0742
Hexarelin
LGD-3033
Sermorelin
Local Anesthetic powder
Oxytocin
Benzocaine
TB500(Thymosin Beta)
Benzocaine Hcl
pentadecapeptide BPC 157
Lidocaine
HGH Fragment 176-191
Lidocaine Hydrochloride
Triptorelin
Procaine
Tesamorelin
Procaine hydrochloride
Gonadorelin
Dyclonine Hydrochloride
DSIP
bupivacaine
Selank
Levobupivacaine Hydrochloride
Epitalon (CAS:307297-39-8)
Propitocaine/prilocaine
follisttatin 344
Propitocaine hydrochloride
Â
Proparacaine hydrochloride
Aviptadil Acetate
Ropivacaine MesylateÂ
GDF-8
Tetracaine HydrochlorideÂ
ACE-031
Tetracaine base
Nootropics
Dibucaine hydrochloride
Â
Articaine HCl
Mirodenafil
Â
Â
Â
Â
Â
Â
Â
Â
G*B*L
Sunifiram
Pharmaceutical Intermediate
DMHA (2-Aminoisoheptane)
T3
coluracetam
T4
Fasoracetam
Ethyl Oleate(EO)
Â
Benzyl Alcohol (BA)
CRL-40,941(Flmodafinil, Lauflumide)
Benzyl Benzoate (BB)
NSI-189
Grape Seed Oil (GSO)
Anamorelin
Â
Â
1,3-Dimethylpentylamine (DMAA)
phenylpiracetam
4-Acetamidophenol (Paracetamol)
Piracetam
Tauroursodeoxycholic Acid (TUDCA)
Aniracetam
Â
Â
4-ANPP
Ashwaganda
Â
Â
glucagon
Phosphatidylserine
Quinidine
Phosphatidylcholine
Galantamine
Alpha-GPC
Â
Our advantage:
Â
1. We have experience in exporting steroids, as you know, EU places much emphasis on them, and you must find a experienced partner who will assure you;
Â
2. Quality: Our company is a professional leading factory in China in pharmaceutical area, We had stable customers and exported to Germany, Spain, UK, USA, Australia, Middle East, and any other countries.
Â
3.We can provide good references about our company. As for the quality of the products, we 're sure they can satisfy you well enough;
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4. Package: Professional packing with professional materials
Â
5. Delivery: We have products in stock, and we will deliver them soon when your PO arrived. Meanwhile we will give you the tracking number in order to make you know the exact location of the products. We will keep track of the product until they arrive you; We choose the best courier service for you, and with the delivery around 5-7 working days.
Â
6. Service: Best Service with after-sales service and consultation.
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Olaparib Quick Details
Olaparib (AZD2281, Ku-0059436) is a selective PARP1 / 2 inhibitor with an IC50 of 5 nM / 1 nM in cell-free assays, 300-fold stronger than that of Tankyrase-1. Phase 3
Chemical Name : 4-(3-(1-(cyclopropanecarbonyl)piperazine-4-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one
MF: C24H23FN4O3
CAS No:763113-22-0
MW: 434.469
Purity: 99%min
Appearance: White Powder
Application: API
Solubility (25°C) : DMSO 86 mg/mL warming (197.94 mM) Water 0.002 mg/mL (0.0 mM) Ethanol <1 mg/mL
Stability :-20ºC Powder , 3 years : -80ºC Soluble in solvents 2years
Type: Antineoplastic Agents
Grade Standard: Medicine Grade
Description
Olaparib is a prescription medicine used to treat advanced Ovarian cancer, It is for patients whose cancerhas certain mutations in the BRCA1 and BRCA2 genes and who have already been treated with at least three other types of chemotherapy.Olaparib is also being studied in the treatment of other types of cancer.
Olapanil is a novel poly-ADP ribose polymerase (PARP) inhibitor, including PARP1, PARP2, and PARP3. PARP mediates a mechanism of DNA repair and plays an important role in DNA damage repair and cell apoptosis. Therefore, the mechanism of DNA damage repair by targeting to cells is mediated by PARP1 and PARCA2 mutant cancer cells Of the critical loopholes in the role, can be used for breast cancer susceptibility gene (BRCA) mutations, platinum-sensitive drug-resistant patients with recurrent severe ovarian cancer maintenance therapy.
Olaparib is a kind of novel poly ADP-ribose polymerase (PARP) inhibitors, including PARP1, PARP2, and PARP3. PARP mediates a DNA-repair mechanism which plays a important role in DNA damage repair and apoptosis, so olaparib specifically targets on the DNA repair mechanism of the targeting cell DNA repair and take effects by attacking the critical vulnerabilities of cancer cells carrying mutations in BRCA1 and BRCA2. Owing to this mechanism, it can be used for the maintenance therapy of patients of severe recurrent ovarian cancer who has breast cancer susceptibility gene (BRCA) mutation as well as being sensitive to platinum drug.
Before order:
Â
1.you could contact us by emial,whatsapp,skype.I am online all the time
2.tell me how many your need and your requirement about products and shipping
3.we offer product COA,Penicillin bottles;cook recipes and others customers tracking numbers and anything if you need.
4.we are accpet Western union,Bank transfer, Bitcion,Money gram,Alipay,Credit card.
Â
Packing Details:
Â
1.Packages are generally dispatched within approximately 2Â days after receipt of payment.
2.After the each shipping we will provide you with: tracking number;pictures with your parcel;
3.Delivery Ways:EMS,HKEMS,TNT,DHL,FedEX,UPS etc.
4.Most countries can arrived within 5-10 days
Â
Â
SARM
Peptides
Ostarine (MK-2866)
MGF
Cardarine (GW-501516)
PEG MGF
Andarine (S4)
CJC-1295 with DAC
Ligandrol (LGD-4033)
CJC-1295 without DAC/GRF(1-29)
Ibutamoren (MK-677)
PT-141
RAD140
MT-2/Melanotan II
SR9009
Â
YK11
GHRP-6
S-23
Ipamorelin
GW-0742
Hexarelin
LGD-3033
Sermorelin
Local Anesthetic powder
Oxytocin
Benzocaine
TB500(Thymosin Beta)
Benzocaine Hcl
pentadecapeptide BPC 157
Lidocaine
HGH Fragment 176-191
Lidocaine Hydrochloride
Triptorelin
Procaine
Tesamorelin
Procaine hydrochloride
Gonadorelin
Dyclonine Hydrochloride
DSIP
bupivacaine
Selank
Levobupivacaine Hydrochloride
Epitalon (CAS:307297-39-8)
Propitocaine/prilocaine
follisttatin 344
Propitocaine hydrochloride
Â
Proparacaine hydrochloride
Aviptadil Acetate
Ropivacaine MesylateÂ
GDF-8
Tetracaine HydrochlorideÂ
ACE-031
Tetracaine base
Nootropics
Dibucaine hydrochloride
Â
Articaine HCl
Mirodenafil
Â
Â
Â
Â
Â
Â
Â
Â
G*B*L
Sunifiram
Pharmaceutical Intermediate
DMHA (2-Aminoisoheptane)
T3
coluracetam
T4
Fasoracetam
Ethyl Oleate(EO)
Â
Benzyl Alcohol (BA)
CRL-40,941(Flmodafinil, Lauflumide)
Benzyl Benzoate (BB)
NSI-189
Grape Seed Oil (GSO)
Anamorelin
Â
Â
1,3-Dimethylpentylamine (DMAA)
phenylpiracetam
4-Acetamidophenol (Paracetamol)
Piracetam
Tauroursodeoxycholic Acid (TUDCA)
Aniracetam
Â
Â
4-ANPP
Ashwaganda
Â
Â
glucagon
Phosphatidylserine
Quinidine
Phosphatidylcholine
Galantamine
Alpha-GPC
Â
Our advantage:
Â
1. We have experience in exporting steroids, as you know, EU places much emphasis on them, and you must find a experienced partner who will assure you;
Â
2. Quality: Our company is a professional leading factory in China in pharmaceutical area, We had stable customers and exported to Germany, Spain, UK, USA, Australia, Middle East, and any other countries.
Â
3.We can provide good references about our company. As for the quality of the products, we 're sure they can satisfy you well enough;
Â
4. Package: Professional packing with professional materials
Â
5. Delivery: We have products in stock, and we will deliver them soon when your PO arrived. Meanwhile we will give you the tracking number in order to make you know the exact location of the products. We will keep track of the product until they arrive you; We choose the best courier service for you, and with the delivery around 5-7 working days.
Â
6. Service: Best Service with after-sales service and consultation.
Â
99% Purity API Pharmceutcial Material Olaparib for Breast Cancer Treatment CAS 763113-22-0
Model NO.: 3000
Trademark: YJ-Pharm
Transport Package: Cartoon
Specification: 1kg/foil bag
Origin: China
HS Code: 3201
Model NO.: 3000
Trademark: YJ-Pharm
Transport Package: Cartoon
Specification: 1kg/foil bag
Origin: China
HS Code: 3201
Olaparib Quick Details