Release date: 2008-04-16 China successfully developed the first generation of biodegradable stents. At the 2008 China Interventional Cardiology Conference held recently, the clinical trial results of China's first biodegradable stent, the domestic EXCEL rapamycin eluting stent, were released. Numerous eyes – After the largest multi-center clinical registry study (CREATE study) in China, the stent has been shown to reduce both restenosis rates and reduce late thrombosis.
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Professor Yan Yaling, the head of the research department and the Institute of Cardiovascular Diseases of the General Hospital of Shenyang Military Region, said that this is the first biodegradable drug-coated stent developed in China and uses biodegradable polylactic acid as a drug-loading layer. The drug can be degraded into water and carbon dioxide 3-6 months after implantation in the body, so the original drug stent becomes a bare metal stent. Therefore, this stent has better biocompatibility and safety, and can reduce the incidence of restenosis and late thrombosis. A total of 59 centers from 4 countries participated in the study, including 2077 patients with coronary heart disease, and 12 months of clinical follow-up and angiographic review results. The evidence-based medical evidence was solid.
For the first time, the scaffold adopts biodegradable coating materials and the design and process of single-sided coating on the luminal cavity side. When it is not inferior to the efficacy of foreign products, its price is only 1/1 of the first generation of similar foreign products. 2 or so, the vast majority of patients with coronary heart disease can afford, plus the shortening of the use of two antiplatelet drugs after surgery, greatly alleviating the price barriers for patients to see expensive. ——Shanghai Medical Device Industry Association
