Dry granulation is a new type of granulation process, which has been applied and developed rapidly in the pharmaceutical industry at home and abroad in recent years. With the further promotion and application of the dry granulation industry in the pharmaceutical industry, the market demand for related technical equipment also shows an expanding trend.
Dry granulation technology is a major strategic innovation in granulation technology. This model realizes the conversion of the pig farms of dealers and approved pellets into pellet processing plants, eliminating many intermediate links and reducing many intermediate costs. For example: transportation costs, marketing expenses, processing costs, etc., have improved their terminal competitiveness.
Dry granulation is environmentally friendly and clean, which saves the dry environment and reduces pollution emissions. It is one of the most widely used pharmaceutical processes.
Dry granulator is more in line with current pharmaceutical production requirements
Dry granulator mainly consists of conveying system, reversing conveying system, extrusion system, crushing system, front cover system, water cooling system, granule system, hydraulic system, body combination, cover plate combination, rotating screen system, etc. Part of the composition, working in a completely sealed state, and all parts in contact with materials are easy to disassemble and clean, effectively preventing dust leakage, reducing the possibility of pollution, reducing the purification area, and more in line with the GMP requirements for pharmaceutical production.
At present, there are many domestic manufacturers of dry granulators, and domestically produced equipment can basically meet the needs of the domestic market. However, due to the lack of investment in technology research and development and innovation, domestically produced equipment still has poor stability and high failure rate. The main problems are: bad roll, water leakage, roll misalignment, large dust production, low yield, difficult to clean, Unstable pressure and other issues.
Experts pointed out that the dry granulation process is a new granulation technology that has emerged in recent years. Its advantage is that it can be directly granulated after adding appropriate amount of excipients in traditional Chinese medicine extract powder, without the processes of wetting, mixing and drying. The process is simple and effective. Guarantee the quality of Chinese medicine. With the continuous expansion of the domestic pharmaceutical industry, especially the continuous advancement of the industrialization of traditional Chinese medicine, the dry granulation process and equipment will be further promoted. Domestic related production enterprises should strengthen technology research and development as early as possible, improve the existing problems of domestic equipment, and better meet the needs of the market.