Brief description of preventive maintenance of water systems in pharmaceutical companies

Abstract: Starting from the relationship between preventive maintenance and preventive maintenance, the content of water system prevention work is elaborated, and the key points to be paid attention to in the work are pointed out.

Keywords: pharmaceuticals; public works; water systems; preventive maintenance. As the output of enterprises further increases, the loss of production due to public media cannot be ignored. Therefore, in order to ensure the normal operation of the process medium and ensure the normal production of the production workshop, the preventive maintenance work of public works equipment has become a key factor. The water system is the focus of public works, and this paper focuses on it.

1 Improve the preventive awareness Preventive maintenance: refers to the main method of checking and maintaining the performance and safety of the equipment before the fault occurs, ensuring the efficient operation of the equipment and the normal supply of the medium to prevent the fault from occurring.

Preventive maintenance: Early detection and early repair of abnormalities in equipment is an advanced repair.

Preventive maintenance and maintenance are complementary. From the perspective of relationship, preventive maintenance is a kind of preventive prevention. It can eliminate the hidden troubles and reduce the failure rate of equipment to the low limit of Zui. Preventive maintenance is an afterthought. Compensation, extending the service life of the equipment, has the advantages of reducing the equipment downtime and avoiding some serious faults. The disadvantage is that it is easy to cause excessive maintenance, resulting in increased costs.

2 Preventive work content 2.1 Preventive maintenance work 2.1.1 Routine maintenance Routine maintenance is a routine maintenance work, which is generally done by the user. It generally includes checking the external cleaning work, the installation and fixing conditions, the lubrication situation, the instrument, the indicator light, and the operation of the instrument.

For the water system: (1) cleaning of the flocculant plus medicine box, adjustment of the dosing pump to ensure the effect; (2) cleaning of the sodium hydrogen sulfite plus chemical tank, adjustment of the dosing pump to ensure the effect; (3) ) Mechanical filter, activated carbon filter valves, switches, normal operation; (4) softener sodium chloride water tank cleaning, to ensure the effect; (5) security filter installation and fixed, interface gasket replacement; (6) The normal operation of the water supply and concentrated water valves of the first-stage reverse osmosis membrane, the parameters of the high pressure pump are normal, the switch is in normal operation; (7) the normal current of the EDI, the voltage and the normal operation of the control button; (8) the interface of each valve of the distilled water, The temperature difference is normal and the normal operation of the control system.

2.1.2 Periodic maintenance Regular maintenance refers to the periodic inspection and maintenance of the accuracy, performance and safety of the system. This work is done by the general technical staff, mainly based on the necessary maintenance of the manual and the manufacturer's information. Current SOP regulations.

For the water system: (1) mechanical filter, activated carbon filter 1.5 years replacement or replacement, to ensure the effect; (2) security filter, precision filter replacement for 3 months, to ensure the effect; (3) softener, mixed The bed resin regeneration cycle becomes shorter and needs to be changed accordingly for replacement; (4) the first-stage reverse osmosis membrane utilization rate is 65% to 75%, and the salt rejection rate is >96%. If it is out of range, it needs to be changed accordingly; (5) The maintenance of the EDI module, voltage and current control is the key. The principle is that the voltage is lower and the current is larger. When the parameters appear to have large voltage and low current, and the water and concentrated water pressure difference is large, the EDI regeneration and cleaning are required; (6) The key equipment affecting the water system is the chiller, and the chiller should be backwashed regularly. Ensure the heat transfer effect of the distilled water machine; (7) Maintenance of the pretreatment part is the key, it is the protection of the reverse osmosis membrane, and it is recommended to increase the SDI (contamination index) in the current water system.

2.2 Preventive maintenance work 2.2.1 Equipment status monitoring The equipment system has a variety of status parameter prompts, which are compared with normal operating parameters. Before using the machine, discover and eliminate hidden dangers in time to keep the equipment in good working condition.

For the water system: (1) the pressure difference between the two ends of the original water pump; (2) the pressure difference between the mechanical filter, the activated carbon filter and the softener; (3) the rate of each dosing box, the dosing concentration; 4) Pressure difference at both ends of the security filter, water production of primary reverse osmosis, pressure difference of concentrated water, conductivity; (5) Voltage, current and conductivity of produced water, concentrated water conductivity, flow rate and pressure difference; (6) The temperature of the distilled water machine is extremely poor, the conductivity of the water production; (7) the temperature of the chiller.

2.2.2 System Special Inspection Workshop The professional personnel will check the key parameters of the system and check the completion of the PDCA control. To do a good job of preventive inspection of equipment, it is necessary to set specific inspection content standards and inspection periods for each type of equipment.

For the water system, it is divided into the following parts:

2.2.2.1 Mechanical inspection and fastening, pipeline inspection (1) Installation and connection of first-stage reverse osmosis, shape and aging of support members, especially for security filters and precision filters; (2) for each sensor Whether the position is changed or loose; (3) Whether the installation around the pump and the pipeline is tight, and the key parts should be checked with a torque wrench; (4) Mechanical inspection of each fastener is an important part of preventive maintenance. one.

2.2.2.2 Distribution system (1) Whether the wire and cable and the pipeline are connected for twisting or tying, whether the lashing is loose, etc.; (2) Dust of the power distribution cabinet; (3) Normal operation of the electrical protection device; (4) Motor of the cooling tower Line inspection; (5) Inspection of the inverter.

2.2.2.3 Inspection of key components (1) Inspection of circulating pump; (2) Power module; (3) Inspection of effluent of group membrane, especially differential pressure; (4) EDI control keys and water quality inspection, especially current and voltage (5) Inspection of the chiller.

2.2.2.4 Easy to lose parts Inspection and replacement parts and accessories (1) gaskets, clamps; (2) probes; (3) circulation pumps; (4) filter elements; (5) power modules.

2.2.3 Preventive work after faulty repairs Preventive work is performed on the repaired equipment. The purpose is to analyze the cause of the fault, avoid similar situations, eliminate all factors that may cause equipment failure, and ensure safe and efficient operation of the equipment.

The main contents are as follows: (1) Improve the equipment file and form a record after each repair; (2) Pay attention to the maintenance effect. After each repair, the workshop indicates that the maintenance effect is reviewed to achieve PDCA control; (3) resource sharing is achieved. Add “Maintenance Set” after each repair, and concentrate on at least quarterly to avoid similar problems.

3 Conclusion Preventive maintenance of the public works water system is an important measure to ensure the good operation of the water system. To prevent preventive maintenance, it is necessary to have a full understanding of the water system, and learn to use the system analysis method to carry out each link of the water system. Analysis, any factor that may affect the operation of the water system can not be ignored.

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