The pharmacological effects of Buddlejae

Pharmacological effects

Hedgehog is similar to quercetin and has a vitamin P-like effect. Oral administration of 25 to 100 mg/kg to mice can reduce formaldehyde inflammation; 50 to 100 mg/kg can also reduce the permeability and brittleness of skin and intestinal blood vessels. The tension in the rat isolated small intestine caused by cesium chloride, histamine, acetylcholine, etc. increased, and hedgehog also had some antispasmodic effects. If injected into the rat small intestine (40 mg / kg) or rabbit intravenous injection (10 ~ 25 mg / kg), can make a brief, mild increase in bile secretion, relaxation of the bile duct smooth muscle. Intravenous injection of 25 mg/kg to rabbits allowed a slight increase in urine volume (75%) in 25-30 minutes. It does not affect the sleep time caused by cyclamate in normal rats, but it can shorten the sleep time in rats with carbon tetrachloride. Robinicin is not toxic and the median lethal dose in mice is 933 mg/kg. In mice isolated on the small intestine specimens, caused by acetylcholine, hedgehog spasmolysis efficacy of 75% papaverine.


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