Cancer treatment is gradually entering a "precise" era, and research on genetic testing and immunotherapy is endless. However, the concept of precision treatment is rarely reflected in traditional treatments such as radiotherapy. Our impression of radiotherapy is always “indiscriminate attackâ€, and there are also a few people who believe that radiotherapy “does more harm than goodâ€. Dr. Jacques Bernier Javier F. Dr. Torres-Roca But as early as 2004, Dr. Jacques Bernier and his colleagues from Switzerland published an article in the journal Nature Review Cancer. They believe that the development of radiation oncology is now at a turning point. We need to improve our technology, look at molecular biology and genetics, and more accurately 'target the target'." Today, more than a decade later, a group of scientists from the Moffitt Cancer Center published a study in the Lancet Oncology magazine, which developed a new genomics model that allows for radiation therapy. Become "personalized." In the early period, research author Javier F. Dr. Torres-Roca led a team of researchers to develop a gene-based radiosensitivity index (RSI), starting with 10 specific genes (AR, c-Jun, STAT1, PKC-beta, RelA, cABL, SUMO1, PAK2). The expression levels of HDAC1, and IRF1) were tested and then a mathematical formula was used to derive a value representing the sensitivity of the tumor to radiation therapy. The researchers performed validation in patients with rectal cancer, esophageal cancer, breast cancer, head and neck cancer, glioblastoma, pancreatic cancer, and metastatic colorectal cancer. They found that patients with high RSI had significantly better radiotherapy. Therefore, the researchers determined that their next step is to use this result to derive a model that can quantify the "radiation treatment effect." Agaricus Blazei Extract,Matsutake Mushroom Extract,Tricholoma Matsutake,Agaricus Mushroom Extract Shaanxi Zhongyi Kangjian Biotechnology Co.,Ltd , https://www.zhongyibiology.com
